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Isabelle Sermet-Gaudelus

Institut Necker Enfants Malades, Université Paris Cité, Paris France

Isabelle Sermet-Gaudelus is a professor in Paediatrics at the Necker-Enfants Malades Hospital, and group leader at INSERM, Paris France. She graduated from the University Paul Sabatier, Toulouse, France, and undertook clinical trainings in Paediatrics in Paris, Assistance Publique Hopitaux de Paris. She became involved in Cystic Fibrosis during her fellowship under the supervision of Pr G Lenoir. She is now the head of the paediatric Cystic Fibrosis centre at the Necker-Enfants Malades Hospital. She has been engaged for several years in a programme of phenotype-genotype studies using epithelial electrophysiological measurements. She runs a clinic which accepts referrals from throughout France for questionable diagnosis for CF. She works closely on a number of commercially-sponsored clinical trials in CF, largely involving novel small-molecules directed at CFTR function. She coordinates the French pediatric cohort of patients treated with CFTR modulators, including infants. As such, she has implemented a biobank of sputum and chest CT collected longitudinally in treated patients and of primary nasal cells of patients with various CFTR mutations and investigates factors driving the response to CFTR modulators in children. She is the head of the standardization committee of the European Clinical Trial Network. She leads a research laboratory at INSERM, Institut Necker Enfants Malades, whose main focus is understanding molecular mechanisms of CFTR modulation.
She has 322 publications indexed in pubmed
H Factor : 60 ; Complete list of publications : https://scholar.google.com/citations?hl=fr&user=lqtC7KwAAAAJ

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