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Session includes an in person invitee/speaker with CF

Symposium

NTR

SW/PSYCH

CLIN

S17-- GI Symptoms in the Era of HEMT: Special Focus on Disorders of the Gut-Brain Axis

Friday, October 9, 2026
2:30 PM - 4:30 PM EDT
This multidisciplinary symposium will explore persistent gastrointestinal symptoms in cystic fibrosis (CF) in the era of highly effective modulator therapies (HEMT). While malabsorption has historically been the main focus, many people with CF continue to experience significant GI symptom burden despite improved nutritional status. The session will examine varying mechanisms including dysmotility, visceral hypersensitivity, altered gut microbiota, constipation syndromes, small intestinal bacterial overgrowth, and disorders of gut–brain interaction, as well as the influence of stress, trauma, and psychological wellbeing on symptom perception and quality of life.

Through an integrated and patient-centered approach, the session will highlight the complex interplay between the gastrointestinal tract, nervous system, nutrition, and emotional health, while considering practical multidisciplinary strategies for assessment and management.