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Symposium

CLIN

S28-- When Modulators Don't Make It Simple: Managing the Gaps

Saturday, October 10, 2026
10:15 AM - 12:15 PM EDT
At the end of the session, the participants should gain knowledge in gaps in prescription of CFTR modulators.
This includes inequity of access at the worldwide level and factors driving individual response such as pharmacokinetic, CFTR genotype, disease stage, environment, and other host modifiers.

Presentation Order:



1. Gaps in Access to CFTR Modulators – Presented by Marco Zampoli

2. Contributors to the Heterogeneity of CFTR Modulator Response – Presented by Damian Downey

3. Disparities in Response to CFTR Modulators: From Mechanistic Insights to Targeted Therapies – Presented by Isabelle Sermet-Gaudelus

4. Drug Exposure, Response and Tolerance to CFTR Modulators – Presented by Jennifer Guimbellot