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Session includes an in person invitee/speaker with CF

Symposium

EPP

S25-- One Organ Two Jobs: Understanding the Role of the Endocrine & Exocrine Pancreas in CF

Saturday, October 10, 2026
10:15 AM - 12:15 PM EDT
This symposium explores the dual roles of the pancreas in cystic fibrosis, highlighting how dysfunction in both the exocrine and endocrine compartments contributes to disease burden. We will examine the pathophysiology of exocrine pancreatic insufficiency and its impact on digestion, nutrition, and growth, alongside emerging insights into islet cell dysfunction and cystic fibrosis–related diabetes (CFRD). The session will emphasize how these two systems are interconnected, sharing developmental origins, structural support, and vulnerability to CFTR-related damage. Recent advances in CFTR modulator therapy and their differential effects on pancreatic function will also be discussed. Together, this talk aims to provide a comprehensive, clinically relevant perspective on managing pancreatic disease across the CF lifespan.